Welcome to MOCR-DB

About MOCR-DB

• The Multi-Omics Causal Resource Database (MOCR-DB) is an integrated resource for investigating genetic correlation, causal inference, and functional interpretation across complex traits. It provides a platform to explore phenotype-to-phenotype genetic relationships and phenotype-to-gene associations with functional mechanisms, leveraging large-scale genomic data.
• MOCR-DB integrates summary statistics from large-scale resources, including FinnGen, UK Biobank, and COVID-19 HGI.
• The current version includes:
  • ~600 GWAS datasets across diverse traits;
  • ~24,000 MR results (with ~1,200 nominally significant);
  • ~33,000 LDSC trait pairs (with ~13,000 showing significant correlation);
  • ~740,000 significant SMR gene-trait associations (based on xQTLs data).
• An AI-assisted module provides plain-language summaries to contextualize statistical findings.
• MOCR-DB supports network construction to visualize shared genetic architecture and functional mediators across traits.